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Protease activity in single-chain prekallikrein

Prekallikrein (PK) is the precursor of the trypsin-like plasma protease kallikrein (PKa), which cleaves kininogens to release bradykinin and converts the protease precursor factor XII (FXII) to the enzyme FXIIa. PK and FXII undergo reciprocal conversion to their active forms (PKa and FXIIa) by a pro...

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Detalhes bibliográficos
Publicado no:Blood
Main Authors: Ivanov, Ivan, Verhamme, Ingrid M., Sun, Mao-fu, Mohammed, Bassem, Cheng, Qiufang, Matafonov, Anton, Dickeson, S. Kent, Joseph, Kusumam, Kaplan, Allen P., Gailani, David
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7033373/
https://ncbi.nlm.nih.gov/pubmed/31800958
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood.2019002224
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