Proteolytic properties of single-chain factor XII: a mechanism for triggering contact activation

When blood is exposed to variety of artificial surfaces and biologic substances, the plasma proteins factor XII (FXII) and prekallikrein undergo reciprocal proteolytic conversion to the proteases αFXIIa and α-kallikrein by a process called contact activation. These enzymes contribute to host-defense...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Blood
Egile Nagusiak: Ivanov, Ivan, Matafonov, Anton, Sun, Mao-fu, Cheng, Qiufang, Dickeson, S. Kent, Verhamme, Ingrid M., Emsley, Jonas, Gailani, David
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society of Hematology 2017
Gaiak:
Thrombosis and Hemostasis
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5356457/
https://ncbi.nlm.nih.gov/pubmed/28069606
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2016-10-744110
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