A conserved inter-domain communication mechanism regulates the ATPase activity of the AAA-protein Drg1

AAA-ATPases fulfil essential roles in different cellular pathways and often act in form of hexameric complexes. Interaction with pathway-specific substrate and adaptor proteins recruits them to their targets and modulates their catalytic activity. This substrate dependent regulation of ATP hydrolysi...

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Udgivet i:Sci Rep
Main Authors: Prattes, Michael, Loibl, Mathias, Zisser, Gertrude, Luschnig, Daniel, Kappel, Lisa, Rössler, Ingrid, Grassegger, Manuela, Hromic, Altijana, Krieger, Elmar, Gruber, Karl, Pertschy, Brigitte, Bergler, Helmut
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2017
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5356007/
https://ncbi.nlm.nih.gov/pubmed/28303975
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep44751
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