Cytoplasmic Recycling of 60S Preribosomal Factors Depends on the AAA Protein Drg1

Allelic forms of DRG1/AFG2 confer resistance to the drug diazaborine, an inhibitor of ribosome biogenesis in Saccharomyces cerevisiae. Our results show that the AAA-ATPase Drg1 is essential for 60S maturation and associates with 60S precursor particles in the cytoplasm. Functional inactivation of Dr...

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Bibliografische gegevens
Hoofdauteurs: Pertschy, Brigitte, Saveanu, Cosmin, Zisser, Gertrude, Lebreton, Alice, Tengg, Martin, Jacquier, Alain, Liebminger, Eva, Nobis, Berthold, Kappel, Lisa, van der Klei, Ida, Högenauer, Gregor, Fromont-Racine, Micheline, Bergler, Helmut
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Microbiology (ASM) 2007
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2099225/
https://ncbi.nlm.nih.gov/pubmed/17646390
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00668-07
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