Rlp24 activates the AAA-ATPase Drg1 to initiate cytoplasmic pre-60S maturation

Formation of eukaryotic ribosomes is driven by energy-consuming enzymes. The AAA-ATPase Drg1 is essential for the release of several shuttling proteins from cytoplasmic pre-60S particles and the loading of late joining proteins. However, its exact role in ribosome biogenesis has been unknown. Here w...

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Bibliografiske detaljer
Main Authors: Kappel, Lisa, Loibl, Mathias, Zisser, Gertrude, Klein, Isabella, Fruhmann, Gernot, Gruber, Christof, Unterweger, Stefan, Rechberger, Gerald, Pertschy, Brigitte, Bergler, Helmut
Format: Artigo
Sprog:Inglês
Udgivet: The Rockefeller University Press 2012
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Research Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3514788/
https://ncbi.nlm.nih.gov/pubmed/23185031
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201205021
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