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Antifibrotic effect of pirfenidone in a mouse model of human nonalcoholic steatohepatitis
Non-alcoholic steatohepatitis (NASH) is characterized by steatosis with lobular inflammation and hepatocyte injury. Pirfenidone (PFD) is an orally bioavailable pyridone derivative that has been clinically used for the treatment of idiopathic pulmonary fibrosis. However, it remains unknown whether PF...
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| Publicado no: | Sci Rep |
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| Main Authors: | , , , , , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5355985/ https://ncbi.nlm.nih.gov/pubmed/28303974 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep44754 |
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