HIV Controllers Exhibit Enhanced Frequencies of Major Histocompatibility Complex Class II Tetramer(+) Gag-Specific CD4(+) T Cells in Chronic Clade C HIV-1 Infection

Immune control of viral infections is heavily dependent on helper CD4(+) T cell function. However, the understanding of the contribution of HIV-specific CD4(+) T cell responses to immune protection against HIV-1, particularly in clade C infection, remains incomplete. Recently, major histocompatibili...

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Publicado en:J Virol
Autores principales: Laher, Faatima, Ranasinghe, Srinika, Porichis, Filippos, Mewalal, Nikoshia, Pretorius, Karyn, Ismail, Nasreen, Buus, Søren, Stryhn, Anette, Carrington, Mary, Walker, Bruce D., Ndung'u, Thumbi, Ndhlovu, Zaza M.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2017
Materias:
Pathogenesis and Immunity
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5355603/
https://ncbi.nlm.nih.gov/pubmed/28077659
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02477-16
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