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Mosaic HIV-1 Gag antigens can be Processed and Presented to human HIV-specific CD8+ T cells

Polyvalent “mosaic” HIV immunogens offer a potential solution for generating vaccines that can elicit immune responses against genetically diverse viruses. However, it is unclear whether key T cell epitopes can be processed and presented from these synthetic antigens and recognized by epitope-specif...

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Bibliografiske detaljer
Main Authors: Ndhlovu, Zaza M, Piechocka-Trocha, Alicja, Vine, Seanna, McMullen, Ashley, Koofhethile, Kegakilwe C, Goulder, Phillip JR, Ndung’u, Thumbi, Barouch, Dan H, Walker, Bruce D
Format: Artigo
Sprog:Inglês
Udgivet: 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3129742/
https://ncbi.nlm.nih.gov/pubmed/21576505
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1004231
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