Elite Controllers with Low to Absent Effector CD8(+) T Cell Responses Maintain Highly Functional, Broadly Directed Central Memory Responses

Analyses of the breadth and specificity of virus-specific CD8(+) T cell responses associated with control of HIV have largely relied on measurement of cytokine secretion by effector T cells. These have resulted in the identification of HIV elite controllers with low or absent responses in which non-...

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Detalhes bibliográficos
Main Authors: Ndhlovu, Zaza M., Proudfoot, Jacqueline, Cesa, Kevin, Alvino, Donna Marie, McMullen, Ashley, Vine, Seanna, Stampouloglou, Eleni, Piechocka-Trocha, Alicja, Walker, Bruce D., Pereyra, Florencia
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2012
Assuntos:
Pathogenesis and Immunity
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3393560/
https://ncbi.nlm.nih.gov/pubmed/22514340
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00531-12
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