High-dimensional immunomonitoring models of HIV-1–specific CD8 T-cell responses accurately identify subjects achieving spontaneous viral control

The development of immunomonitoring models to determine HIV-1 vaccine efficacy is a major challenge. Studies suggest that HIV-1–specific CD8 T cells play a critical role in subjects achieving spontaneous viral control (HIV-1 controllers) and that they will be important in immune interventions. Howev...

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Autors principals: Ndhlovu, Zaza M., Chibnik, Lori B., Proudfoot, Jacqueline, Vine, Seanna, McMullen, Ashley, Cesa, Kevin, Porichis, Filippos, Jones, R. Brad, Alvino, Donna Marie, Hart, Meghan G., Stampouloglou, Eleni, Piechocka-Trocha, Alicja, Kadie, Carl, Pereyra, Florencia, Heckerman, David, De Jager, Philip L., Walker, Bruce D., Kaufmann, Daniel E.
Format: Artigo
Idioma:Inglês
Publicat: American Society of Hematology 2013
Matèries:
Immunobiology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3563365/
https://ncbi.nlm.nih.gov/pubmed/23233659
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2012-06-436295
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