The Breadth of Expandable Memory CD8(+) T Cells Inversely Correlates with Residual Viral Loads in HIV Elite Controllers

Previous studies have shown that elite controllers with minimal effector T cell responses harbor a low-frequency, readily expandable, highly functional, and broadly directed memory population. Here, we interrogated the in vivo relevance of this cell population by investigating whether the breadth of...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Ndhlovu, Zaza M., Stampouloglou, Eleni, Cesa, Kevin, Mavrothalassitis, Orestes, Alvino, Donna Marie, Li, Jonathan Z., Wilton, Shannon, Karel, Daniel, Piechocka-Trocha, Alicja, Chen, Huabiao, Pereyra, Florencia, Walker, Bruce D.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2015
Assuntos:
Cellular Response to Infection
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4621138/
https://ncbi.nlm.nih.gov/pubmed/26269189
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01527-15
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