A novel ZEB1/HAS2 positive feedback loop promotes EMT in breast cancer

Cancer metastasis is the main reason for poor patient survival. Tumor cells delaminate from the primary tumor by induction of epithelial-mesenchymal transition (EMT). EMT is mediated by key transcription factors, including ZEB1, activated by tumor cell interactions with stromal cells and the extrace...

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Pubblicato in:Oncotarget
Autori principali: Preca, Bogdan-Tiberius, Bajdak, Karolina, Mock, Kerstin, Lehmann, Waltraut, Sundararajan, Vignesh, Bronsert, Peter, Matzge-Ogi, Alexandra, Orian-Rousseau, Véronique, Brabletz, Simone, Brabletz, Thomas, Maurer, Jochen, Stemmler, Marc P.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Impact Journals LLC 2017
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Research Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5355283/
https://ncbi.nlm.nih.gov/pubmed/28086235
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.14563
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