Inhibition of CDK8 mediator kinase suppresses estrogen dependent transcription and the growth of estrogen receptor positive breast cancer

Hormone therapy targeting estrogen receptor (ER) is the principal treatment for ER-positive breast cancers. However, many cancers develop resistance to hormone therapy while retaining ER expression. Identifying new druggable mediators of ER function can help to increase the efficacy of ER-targeting...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: McDermott, Martina S.J., Chumanevich, Alexander A., Lim, Chang-uk, Liang, Jiaxin, Chen, Mengqian, Altilia, Serena, Oliver, David, Rae, James M., Shtutman, Michael, Kiaris, Hippokratis, Győrffy, Balázs, Roninson, Igor B., Broude, Eugenia V.
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2017
Assuntos:
Priority Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5355036/
https://ncbi.nlm.nih.gov/pubmed/28147342
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.14894
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados