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Potent CD4(+) T cell-associated antitumor memory responses induced by trifunctional bispecific antibodies in combination with immune checkpoint inhibition

Combinatorial approaches of immunotherapy hold great promise for the treatment of malignant disease. Here, we examined the potential of combining an immune checkpoint inhibitor and trifunctional bispecific antibodies (trAbs) in a preclinical melanoma mouse model using surrogate antibodies of Ipilimu...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Oncotarget
Päätekijät: Deppisch, Nina, Ruf, Peter, Eißler, Nina, Lindhofer, Horst, Mocikat, Ralph
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Impact Journals LLC 2016
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5354850/
https://ncbi.nlm.nih.gov/pubmed/27966460
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.13888
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