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Potential of the Trifunctional Bispecific Antibody Surek Depends on Dendritic Cells: Rationale for a New Approach of Tumor Immunotherapy

Trifunctional bispecific antibodies (trAbs) used in tumor immunotherapy have the unique ability to recruit T cells toward antigens on the tumor cell surface and, moreover, to activate accessory cells through their immunoglobulin Fc region interacting with activating Fcγ receptors. This scenario give...

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Detalhes bibliográficos
Main Authors: Eissler, Nina, Mysliwietz, Josef, Deppisch, Nina, Ruf, Peter, Lindhofer, Horst, Mocikat, Ralph
Formato: Artigo
Idioma:Inglês
Publicado em: ScholarOne 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3646096/
https://ncbi.nlm.nih.gov/pubmed/23552725
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2119/molmed.2012.00140
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