Structural and functional characterization of the trifunctional antibody catumaxomab

The Triomab(®) family of trifunctional, bispecific antibodies that maintain an IgG-like shape are novel tumor targeting agents. These chimeras consist of two half antibodies, each with one light and one heavy chain, that originate from parental mouse IgG2a and rat IgG2b isotypes. This combination al...

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Autores principales: Chelius, Dirk, Ruf, Peter, Plöscher, Matthias, Liedtke, Reinhard, Gansberger, Eva, Hess, Juergen, Wasiliu, Michael, Lindhofer, Horst
Formato: Artigo
Lenguaje:Inglês
Publicado: Landes Bioscience 2010
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Reports
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2881257/
https://ncbi.nlm.nih.gov/pubmed/20418662
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