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Characterisation of the new EpCAM-specific antibody HO-3: implications for trifunctional antibody immunotherapy of cancer

Epithelial cell adhesion molecule EpCAM is a transmembrane glycoprotein that is frequently overexpressed in a variety of carcinomas. This pan-carcinoma antigen has served as the target for a plethora of immunotherapies. Innovative therapeutic approaches include the use of trifunctional antibodies (t...

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Detalhes bibliográficos
Main Authors: Ruf, P, Gires, O, Jäger, M, Fellinger, K, Atz, J, Lindhofer, H
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2360319/
https://ncbi.nlm.nih.gov/pubmed/17622246
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6603881
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