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Potent CD4(+) T cell-associated antitumor memory responses induced by trifunctional bispecific antibodies in combination with immune checkpoint inhibition

Combinatorial approaches of immunotherapy hold great promise for the treatment of malignant disease. Here, we examined the potential of combining an immune checkpoint inhibitor and trifunctional bispecific antibodies (trAbs) in a preclinical melanoma mouse model using surrogate antibodies of Ipilimu...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Deppisch, Nina, Ruf, Peter, Eißler, Nina, Lindhofer, Horst, Mocikat, Ralph
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5354850/
https://ncbi.nlm.nih.gov/pubmed/27966460
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.13888
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