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Loss of RUNX3 expression inhibits bone invasion of oral squamous cell carcinoma

High recurrence and lower survival rates in patients with oral squamous cell carcinoma (OSCC) are associated with its bone invasion. We identified the oncogenic role of RUNX3 during bone invasion by OSCC. Tumor growth and the generation of osteolytic lesions were significantly inhibited in mice that...

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Bibliografiske detaljer
Udgivet i:Oncotarget
Main Authors: Park, Junhee, Kim, Hyun-Jeong, Kim, Ki Rim, Lee, Sun Kyoung, Kim, Hyungkeun, Park, Kwang-Kyun, Chung, Won-Yoon
Format: Artigo
Sprog:Inglês
Udgivet: Impact Journals LLC 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5354716/
https://ncbi.nlm.nih.gov/pubmed/28030842
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.14071
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