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Loss of RUNX3 expression inhibits bone invasion of oral squamous cell carcinoma

High recurrence and lower survival rates in patients with oral squamous cell carcinoma (OSCC) are associated with its bone invasion. We identified the oncogenic role of RUNX3 during bone invasion by OSCC. Tumor growth and the generation of osteolytic lesions were significantly inhibited in mice that...

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Dettagli Bibliografici
Pubblicato in:Oncotarget
Autori principali: Park, Junhee, Kim, Hyun-Jeong, Kim, Ki Rim, Lee, Sun Kyoung, Kim, Hyungkeun, Park, Kwang-Kyun, Chung, Won-Yoon
Natura: Artigo
Lingua:Inglês
Pubblicazione: Impact Journals LLC 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5354716/
https://ncbi.nlm.nih.gov/pubmed/28030842
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.14071
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