Loss of RUNX3 expression inhibits bone invasion of oral squamous cell carcinoma

High recurrence and lower survival rates in patients with oral squamous cell carcinoma (OSCC) are associated with its bone invasion. We identified the oncogenic role of RUNX3 during bone invasion by OSCC. Tumor growth and the generation of osteolytic lesions were significantly inhibited in mice that...

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Detalles Bibliográficos
Publicado en:Oncotarget
Main Authors: Park, Junhee, Kim, Hyun-Jeong, Kim, Ki Rim, Lee, Sun Kyoung, Kim, Hyungkeun, Park, Kwang-Kyun, Chung, Won-Yoon
Formato: Artigo
Idioma:Inglês
Publicado: Impact Journals LLC 2016
Assuntos:
Research Paper
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5354716/
https://ncbi.nlm.nih.gov/pubmed/28030842
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.14071
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