15-Deoxy-Δ(12,14)-Prostaglandin J(2) Inhibits Osteolytic Breast Cancer Bone Metastasis and Estrogen Deficiency-Induced Bone Loss

Breast cancer is the major cause of cancer death in women worldwide. The most common site of metastasis is bone. Bone metastases obstruct the normal bone remodeling process and aberrantly enhance osteoclast-mediated bone resorption, which results in osteolytic lesions. 15-deoxy-Δ(12,14)-prostaglandi...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Kim, Ki Rim, Kim, Hyun Jeong, Lee, Sun Kyoung, Ma, Gwang Taek, Park, Kwang Kyun, Chung, Won Yoon
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4393227/
https://ncbi.nlm.nih.gov/pubmed/25859665
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0122764
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