Loss of RUNX3 expression promotes cancer‐associated bone destruction by regulating CCL5, CCL19 and CXCL11 in non‐small cell lung cancer

Non‐small cell lung cancer (NSCLC) frequently metastasizes to bone, which is associated with significant morbidity and a dismal prognosis. RUNX3 functions as a tumour suppressor in lung cancer and loss of expression occurs more frequently in invasive lung adenocarcinoma than in pre‐invasive lesions....

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Publicado en:J Pathol
Autores principales: Kim, Hyun‐Jeong, Park, Junhee, Lee, Sun Kyoung, Kim, Ki Rim, Park, Kwang‐Kyun, Chung, Won‐Yoon
Formato: Artigo
Lenguaje:Inglês
Publicado: John Wiley & Sons, Ltd 2015
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Original Papers
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4832375/
https://ncbi.nlm.nih.gov/pubmed/26239696
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/path.4597
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