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Loss of RUNX3 expression promotes cancer‐associated bone destruction by regulating CCL5, CCL19 and CXCL11 in non‐small cell lung cancer

Non‐small cell lung cancer (NSCLC) frequently metastasizes to bone, which is associated with significant morbidity and a dismal prognosis. RUNX3 functions as a tumour suppressor in lung cancer and loss of expression occurs more frequently in invasive lung adenocarcinoma than in pre‐invasive lesions....

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Detalhes bibliográficos
Publicado no:J Pathol
Main Authors: Kim, Hyun‐Jeong, Park, Junhee, Lee, Sun Kyoung, Kim, Ki Rim, Park, Kwang‐Kyun, Chung, Won‐Yoon
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley & Sons, Ltd 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4832375/
https://ncbi.nlm.nih.gov/pubmed/26239696
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/path.4597
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