Llwytho...

Sequence-specific thermodynamic properties of nucleic acids influence both transcriptional pausing and backtracking in yeast

RNA Polymerase II pauses and backtracks during transcription, with many consequences for gene expression and cellular physiology. Here, we show that the energy required to melt double-stranded nucleic acids in the transcription bubble predicts pausing in Saccharomyces cerevisiae far more accurately...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:PLoS One
Prif Awduron: Lukačišin, Martin, Landon, Matthieu, Jajoo, Rishi
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Public Library of Science 2017
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5354634/
https://ncbi.nlm.nih.gov/pubmed/28301878
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0174066
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