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Backtracked and paused transcription initiation intermediate of Escherichia coli RNA polymerase
Initiation is a highly regulated, rate-limiting step in transcription. We used a series of approaches to examine the kinetics of RNA polymerase (RNAP) transcription initiation in greater detail. Quenched kinetics assays, in combination with gel-based assays, showed that RNAP exit kinetics from compl...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Main Authors: | , , , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5087071/ https://ncbi.nlm.nih.gov/pubmed/27729537 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1605038113 |
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