Thermodynamic and kinetic modeling of transcriptional pausing

We present a statistical mechanics approach for the prediction of backtracked pauses in bacterial transcription elongation derived from structural models of the transcription elongation complex (EC). Our algorithm is based on the thermodynamic stability of the EC along the DNA template calculated fr...

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Detalhes bibliográficos
Main Authors: Tadigotla, Vasisht R., Maoiléidigh, Dáibhid Ó, Sengupta, Anirvan M., Epshtein, Vitaly, Ebright, Richard H., Nudler, Evgeny, Ruckenstein, Andrei E.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2006
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1450190/
https://ncbi.nlm.nih.gov/pubmed/16537373
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0600508103
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