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Thermodynamic and kinetic modeling of transcriptional pausing

We present a statistical mechanics approach for the prediction of backtracked pauses in bacterial transcription elongation derived from structural models of the transcription elongation complex (EC). Our algorithm is based on the thermodynamic stability of the EC along the DNA template calculated fr...

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Detaylı Bibliyografya
Asıl Yazarlar: Tadigotla, Vasisht R., Maoiléidigh, Dáibhid Ó, Sengupta, Anirvan M., Epshtein, Vitaly, Ebright, Richard H., Nudler, Evgeny, Ruckenstein, Andrei E.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: National Academy of Sciences 2006
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC1450190/
https://ncbi.nlm.nih.gov/pubmed/16537373
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0600508103
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