Načítá se...

DYRK1B blocks canonical and promotes non-canonical Hedgehog signaling through activation of the mTOR/AKT pathway

Hedgehog (Hh) signaling plays important roles in embryonic development and in tumor formation. Apart from the well-established stimulation of the GLI family of transcription factors, Hh ligands promote the phosphorylation and activation of mTOR and AKT kinases, yet the molecular mechanism underlying...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:Oncotarget
Hlavní autoři: Singh, Rajeev, Dhanyamraju, Pavan Kumar, Lauth, Matthias
Médium: Artigo
Jazyk:Inglês
Vydáno: Impact Journals LLC 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5352201/
https://ncbi.nlm.nih.gov/pubmed/27903983
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.13662
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!