Precursor of amyloid protein in Alzheimer disease undergoes fast anterograde axonal transport.

In the brains of aged humans and cases of Alzheimer disease, deposits of amyloid in senile plaques are located in proximity to nerve processes. The principal component of this extracellular amyloid is beta/A4, a peptide derived from a larger amyloid precursor protein (APP), which is actively express...

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Pubblicato in:	Proc Natl Acad Sci U S A
Autori principali:	Koo, E H, Sisodia, S S, Archer, D R, Martin, L J, Weidemann, A, Beyreuther, K, Fischer, P, Masters, C L, Price, D L
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	National Academy of Sciences 1990
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC53515/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1689489/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.87.4.1561
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