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The expression of the amyloid precursor protein (APP) is regulated by two GC-elements in the promoter.

The structure of the promoter of the human APP gene resembles that of housekeeping genes, with the presence of a GC-rich region and the lack of a canonical TATA box. Since analysis of the expression of the APP gene, especially at the transcriptional level, might reveal factors or elements, which inf...

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Detalles Bibliográficos
Publicado en:Nucleic Acids Res
Principais autores: Pollwein, P, Masters, C L, Beyreuther, K
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 1992
Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC310326/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1738605/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/20.1.63
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