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The expression of the amyloid precursor protein (APP) is regulated by two GC-elements in the promoter.

The structure of the promoter of the human APP gene resembles that of housekeeping genes, with the presence of a GC-rich region and the lack of a canonical TATA box. Since analysis of the expression of the APP gene, especially at the transcriptional level, might reveal factors or elements, which inf...

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Библиографические подробности
Главные авторы: Pollwein, P, Masters, C L, Beyreuther, K
Формат: Artigo
Язык:Inglês
Опубликовано: 1992
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC310326/
https://ncbi.nlm.nih.gov/pubmed/1738605
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