The expression of the amyloid precursor protein (APP) is regulated by two GC-elements in the promoter.
The structure of the promoter of the human APP gene resembles that of housekeeping genes, with the presence of a GC-rich region and the lack of a canonical TATA box. Since analysis of the expression of the APP gene, especially at the transcriptional level, might reveal factors or elements, which inf...
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| Veröffentlicht in: | Nucleic Acids Res |
|---|---|
| Hauptverfasser: | , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Oxford University Press
1992
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| Online-Zugang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC310326/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1738605/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/20.1.63 |
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