Catechol‐O‐Methyltransferase Genotype Modulates Opioid Release in Decision Circuitry

Impulsivity, a risk factor for substance abuse disorders, is modulated by the Val158 variant of the catechol‐O‐methyltransferase (COMT) gene. Rodent studies have shown that opioids enhance impulsivity. Furthermore, alcohol consumption leads to endogenous opioid release in the cortex and nucleus accu...

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Sparad:
Bibliografiska uppgifter
I publikationen:Clin Transl Sci
Huvudupphovsmän: Mitchell, Jennifer M., O'Neil, James P., Jagust, William J., Fields, Howard L.
Materialtyp: Artigo
Språk:Inglês
Publicerad: John Wiley and Sons Inc. 2013
Ämnen:
Research Articles
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5350883/
https://ncbi.nlm.nih.gov/pubmed/24127930
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cts.12075
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