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Catechol‐O‐Methyltransferase Genotype Modulates Opioid Release in Decision Circuitry

Impulsivity, a risk factor for substance abuse disorders, is modulated by the Val158 variant of the catechol‐O‐methyltransferase (COMT) gene. Rodent studies have shown that opioids enhance impulsivity. Furthermore, alcohol consumption leads to endogenous opioid release in the cortex and nucleus accu...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Clin Transl Sci
Päätekijät: Mitchell, Jennifer M., O'Neil, James P., Jagust, William J., Fields, Howard L.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: John Wiley and Sons Inc. 2013
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5350883/
https://ncbi.nlm.nih.gov/pubmed/24127930
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cts.12075
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