Catechol‐O‐Methyltransferase Genotype Modulates Opioid Release in Decision Circuitry

Impulsivity, a risk factor for substance abuse disorders, is modulated by the Val158 variant of the catechol‐O‐methyltransferase (COMT) gene. Rodent studies have shown that opioids enhance impulsivity. Furthermore, alcohol consumption leads to endogenous opioid release in the cortex and nucleus accu...

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Detaylı Bibliyografya
Yayımlandı:Clin Transl Sci
Asıl Yazarlar: Mitchell, Jennifer M., O'Neil, James P., Jagust, William J., Fields, Howard L.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: John Wiley and Sons Inc. 2013
Konular:
Research Articles
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5350883/
https://ncbi.nlm.nih.gov/pubmed/24127930
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cts.12075
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