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Catechol‐O‐Methyltransferase Genotype Modulates Opioid Release in Decision Circuitry
Impulsivity, a risk factor for substance abuse disorders, is modulated by the Val158 variant of the catechol‐O‐methyltransferase (COMT) gene. Rodent studies have shown that opioids enhance impulsivity. Furthermore, alcohol consumption leads to endogenous opioid release in the cortex and nucleus accu...
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| Veröffentlicht in: | Clin Transl Sci |
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| Hauptverfasser: | , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
John Wiley and Sons Inc.
2013
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5350883/ https://ncbi.nlm.nih.gov/pubmed/24127930 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cts.12075 |
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