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Catechol‐O‐Methyltransferase Genotype Modulates Opioid Release in Decision Circuitry
Impulsivity, a risk factor for substance abuse disorders, is modulated by the Val158 variant of the catechol‐O‐methyltransferase (COMT) gene. Rodent studies have shown that opioids enhance impulsivity. Furthermore, alcohol consumption leads to endogenous opioid release in the cortex and nucleus accu...
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| Publicado no: | Clin Transl Sci |
|---|---|
| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley and Sons Inc.
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5350883/ https://ncbi.nlm.nih.gov/pubmed/24127930 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cts.12075 |
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