Network degeneration and dysfunction in presymptomatic C9ORF72 expansion carriers

Hexanucleotide repeat expansions in C9ORF72 are the most common known genetic cause of familial and sporadic frontotemporal dementia and amyotrophic lateral sclerosis. Previous work has shown that patients with behavioral variant frontotemporal dementia due to C9ORF72 show salience and sensorimotor...

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Publicado en:Neuroimage Clin
Main Authors: Lee, Suzee E., Sias, Ana C., Mandelli, Maria Luisa, Brown, Jesse A., Brown, Alainna B., Khazenzon, Anna M., Vidovszky, Anna A., Zanto, Theodore P., Karydas, Anna M., Pribadi, Mochtar, Dokuru, Deepika, Coppola, Giovanni, Geschwind, Dan H., Rademakers, Rosa, Gorno-Tempini, Maria Luisa, Rosen, Howard J., Miller, Bruce L., Seeley, William W.
Formato: Artigo
Idioma:Inglês
Publicado: Elsevier 2016
Assuntos:
Regular Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5349617/
https://ncbi.nlm.nih.gov/pubmed/28337409
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nicl.2016.12.006
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