Wordt geladen...
Hsp90 dependence of a kinase is determined by its conformational landscape
Heat shock protein 90 (Hsp90) is an abundant molecular chaperone, involved in the folding and activation of 60% of the human kinome. The oncogenic tyrosine kinase v-Src is one of the most stringent client proteins of Hsp90, whereas its almost identical homolog c-Src is only weakly affected by the ch...
Bewaard in:
| Gepubliceerd in: | Sci Rep |
|---|---|
| Hoofdauteurs: | , , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
Nature Publishing Group
2017
|
| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5349555/ https://ncbi.nlm.nih.gov/pubmed/28290541 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep43996 |
| Tags: |
Voeg label toe
Geen labels, Wees de eerste die dit record labelt!
|