Prion-specific and surrogate CSF biomarkers in Creutzfeldt-Jakob disease: diagnostic accuracy in relation to molecular subtypes and analysis of neuropathological correlates of p-tau and Aβ42 levels

The differential diagnosis of Creutzfeldt-Jakob disease (CJD) from other, sometimes treatable, neurological disorders is challenging, owing to the wide phenotypic heterogeneity of the disease. Real-time quaking-induced prion conversion (RT-QuIC) is a novel ultrasensitive in vitro assay, which, at va...

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Detalles Bibliográficos
Publicado en:Acta Neuropathol
Main Authors: Lattanzio, Francesca, Abu-Rumeileh, Samir, Franceschini, Alessia, Kai, Hideaki, Amore, Giulia, Poggiolini, Ilaria, Rossi, Marcello, Baiardi, Simone, McGuire, Lynne, Ladogana, Anna, Pocchiari, Maurizio, Green, Alison, Capellari, Sabina, Parchi, Piero
Formato: Artigo
Idioma:Inglês
Publicado: Springer Berlin Heidelberg 2017
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Original Paper
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5348556/
https://ncbi.nlm.nih.gov/pubmed/28205010
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00401-017-1683-0
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