Characterization of Truncated Forms of Abnormal Prion Protein in Creutzfeldt-Jakob Disease

In prion disease, the abnormal conformer of the cellular prion protein, PrP(Sc), deposits in fibrillar protein aggregates in brain and other organs. Limited exposure of PrP(Sc) to proteolytic digestion in vitro generates a core fragment of 19–21 kDa, named PrP27–30, which is also found in vivo. Rece...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Notari, Silvio, Strammiello, Rosaria, Capellari, Sabina, Giese, Armin, Cescatti, Maura, Grassi, Jacques, Ghetti, Bernardino, Langeveld, Jan P. M., Zou, Wen-Quan, Gambetti, Pierluigi, Kretzschmar, Hans A., Parchi, Piero
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2008
Assuntos:
Protein Structure and Folding
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2662149/
https://ncbi.nlm.nih.gov/pubmed/18753138
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M801877200
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados