Genome-wide methylome analysis using MethylCap-seq uncovers 4 hypermethylated markers with high sensitivity for both adeno- and squamous-cell cervical carcinoma

BACKGROUND: Cytology-based screening methods for cervical adenocarcinoma (ADC) and to a lesser extent squamous-cell carcinoma (SCC) suffer from low sensitivity. DNA hypermethylation analysis in cervical scrapings may improve detection of SCC, but few methylation markers have been described for ADC....

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Enregistré dans:
Détails bibliographiques
Publié dans:Oncotarget
Auteurs principaux: Wang, Rong, van Leeuwen, Robert W., Boers, Aniek, Klip, Harry G., de Meyer, Tim, Steenbergen, Renske D. M., van Criekinge, Wim, van der Zee, Ate G. J., Schuuring, Ed, Wisman, G. Bea A.
Format: Artigo
Langue:Inglês
Publié: Impact Journals LLC 2016
Sujets:
Research Paper
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5348351/
https://ncbi.nlm.nih.gov/pubmed/27738327
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.12598
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