Genome-wide methylation profiling identifies hypermethylated biomarkers in high-grade cervical intraepithelial neoplasia

Epigenetic modifications, such as aberrant DNA promoter methylation, are frequently observed in cervical cancer. Identification of hypermethylated regions allowing discrimination between normal cervical epithelium and high-grade cervical intraepithelial neoplasia (CIN2/3), or worse, may improve curr...

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Detalhes bibliográficos
Main Authors: Lendvai, Ágnes, Johannes, Frank, Grimm, Christina, Eijsink, Jasper J.H., Wardenaar, René, Volders, Haukeline H., Klip, Harry G., Hollema, Harry, Jansen, Ritsert C., Schuuring, Ed, Wisman, G. Bea A., van der Zee, Ate G.J.
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2012
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3499328/
https://ncbi.nlm.nih.gov/pubmed/23018867
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/epi.22301
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