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Discovery of new methylation markers to improve screening for cervical intraepithelial neoplasia grade 2/3

BACKGROUND: Assessment of DNA promoter methylation markers in cervical scrapings for the detection of cervical intraepithelial neoplasia (CIN) and cervical cancer is feasible, but finding methylation markers with both high sensitivity as well as high specificity remains a challenge. In this study, w...

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Detalhes bibliográficos
Publicado no:Clin Epigenetics
Main Authors: Boers, A., Wang, R., van Leeuwen, R. W., Klip, H. G., de Bock, G. H., Hollema, H., van Criekinge, W., de Meyer, T., Denil, S., van der Zee, A. G J., Schuuring, E., Wisman, G. B. A.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4784352/
https://ncbi.nlm.nih.gov/pubmed/26962367
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13148-016-0196-3
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