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Discovery of new methylation markers to improve screening for cervical intraepithelial neoplasia grade 2/3

BACKGROUND: Assessment of DNA promoter methylation markers in cervical scrapings for the detection of cervical intraepithelial neoplasia (CIN) and cervical cancer is feasible, but finding methylation markers with both high sensitivity as well as high specificity remains a challenge. In this study, w...

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Detalles Bibliográficos
Publicado en:Clin Epigenetics
Main Authors: Boers, A., Wang, R., van Leeuwen, R. W., Klip, H. G., de Bock, G. H., Hollema, H., van Criekinge, W., de Meyer, T., Denil, S., van der Zee, A. G J., Schuuring, E., Wisman, G. B. A.
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2016
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4784352/
https://ncbi.nlm.nih.gov/pubmed/26962367
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13148-016-0196-3
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