Genome-wide methylome analysis using MethylCap-seq uncovers 4 hypermethylated markers with high sensitivity for both adeno- and squamous-cell cervical carcinoma

BACKGROUND: Cytology-based screening methods for cervical adenocarcinoma (ADC) and to a lesser extent squamous-cell carcinoma (SCC) suffer from low sensitivity. DNA hypermethylation analysis in cervical scrapings may improve detection of SCC, but few methylation markers have been described for ADC....

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Dades bibliogràfiques
Publicat a:Oncotarget
Autors principals: Wang, Rong, van Leeuwen, Robert W., Boers, Aniek, Klip, Harry G., de Meyer, Tim, Steenbergen, Renske D. M., van Criekinge, Wim, van der Zee, Ate G. J., Schuuring, Ed, Wisman, G. Bea A.
Format: Artigo
Idioma:Inglês
Publicat: Impact Journals LLC 2016
Matèries:
Research Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5348351/
https://ncbi.nlm.nih.gov/pubmed/27738327
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.12598
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