Genome-wide methylome analysis using MethylCap-seq uncovers 4 hypermethylated markers with high sensitivity for both adeno- and squamous-cell cervical carcinoma

BACKGROUND: Cytology-based screening methods for cervical adenocarcinoma (ADC) and to a lesser extent squamous-cell carcinoma (SCC) suffer from low sensitivity. DNA hypermethylation analysis in cervical scrapings may improve detection of SCC, but few methylation markers have been described for ADC....

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Publicado en:Oncotarget
Autores principales: Wang, Rong, van Leeuwen, Robert W., Boers, Aniek, Klip, Harry G., de Meyer, Tim, Steenbergen, Renske D. M., van Criekinge, Wim, van der Zee, Ate G. J., Schuuring, Ed, Wisman, G. Bea A.
Formato: Artigo
Lenguaje:Inglês
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5348351/
https://ncbi.nlm.nih.gov/pubmed/27738327
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.12598
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