S-nitrosation on zinc finger motif of PARP-1 as a mechanism of DNA repair inhibition by arsenite

Arsenic, a widely distributed carcinogen, is known to significantly amplify the impact of other carcinogens through inhibition of DNA repair. Our recent work suggests that reactive oxygen/nitrogen species (ROS/RNS) induced by arsenite (AsIII) play an important role in the inhibition of the DNA repai...

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Bibliographische Detailangaben
Veröffentlicht in:Oncotarget
Hauptverfasser: Zhou, Xixi, Cooper, Karen L., Huestis, Juliana, Xu, Huan, Burchiel, Scott W., Hudson, Laurie G., Liu, Ke Jian
Format: Artigo
Sprache:Inglês
Veröffentlicht: Impact Journals LLC 2016
Schlagworte:
Research Paper
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5348335/
https://ncbi.nlm.nih.gov/pubmed/27741521
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.12613
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