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KINETICS AND THERMODYNAMICS OF ZINC(II) AND ARSENIC(III) BINDING TO XPA AND PARP-1 ZINC FINGER PEPTIDES
Inhibition of DNA repair is an established mechanism of arsenic co-carcinogenesis, and may be perpetuated by the binding of As(III) to key zinc finger (zf) DNA repair proteins. Validated molecular targets of As(III) include the first zinc finger domain of Poly (ADP-Ribose) Polymerase 1 (PARP-1), and...
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| Publicado no: | J Inorg Biochem |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5096954/ https://ncbi.nlm.nih.gov/pubmed/27521476 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jinorgbio.2016.08.003 |
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