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S-nitrosation on zinc finger motif of PARP-1 as a mechanism of DNA repair inhibition by arsenite
Arsenic, a widely distributed carcinogen, is known to significantly amplify the impact of other carcinogens through inhibition of DNA repair. Our recent work suggests that reactive oxygen/nitrogen species (ROS/RNS) induced by arsenite (AsIII) play an important role in the inhibition of the DNA repai...
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Publicado no: | Oncotarget |
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Main Authors: | , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Impact Journals LLC
2016
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5348335/ https://ncbi.nlm.nih.gov/pubmed/27741521 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.12613 |
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