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Differential Binding of Monomethylarsonous Acid Compared to Arsenite and Arsenic Trioxide with Zinc Finger Peptides and Proteins

[Image: see text] Arsenic is an environmental toxin that enhances the carcinogenic effect of DNA-damaging agents, such as ultraviolet radiation and benzo[a]pyrene. Interaction with zinc finger proteins has been shown to be an important molecular mechanism for arsenic toxicity and cocarcinogenesis. A...

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Detalhes bibliográficos
Main Authors: Zhou, Xixi, Sun, Xi, Mobarak, Charlotte, Gandolfi, A. Jay, Burchiel, Scott W., Hudson, Laurie G., Liu, Ke Jian
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2014
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3998772/
https://ncbi.nlm.nih.gov/pubmed/24611629
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/tx500022j
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